I don't play allot with nitris, so I'm no expert, but have been around some of the guys that use them. So this is my best understanding of using big shots on NOS.
With direct port/fogger I'd assume you are doing this so you can spray more then through a plate, so you will most likely need larger lines and you will probably want seperate pump and even a tank (1-2 gallons of real high octane ). You could certainly use the same lines and such as you would with a plate if you running the same shot as you would through the plate. All you're doing it branching off after the selonoid ( again, my understanding, don't take that as a fact? ) The people I know running 175 or larger shots have replaced all their stock lines with large braided lines and BIG fuel pumps.
Also, the foggers systems I've seen split the system into right/left side. You're not running each cylinder seperately, but feeding right side/left side using some type of log or distribution. So when your tuning you can jet and montioring right/left bank, not each cylinder.
I'll try to get some pics of my friend's set-up, but here is one off the web that shows what I mean.
http://www.nitrousoutlet.com/installs/install.asp?id=30
If no one on here can give you more a more fact filled answer I'll get in touch with N2ODave or REB17 and get you real answers, both of them have run foggers on the LT1s.